Team USA start Group B against Wales on November 21, followed by England on November 25 and then a crunch match against Iran, which has become one of the hot tickets in Doha because of the political rivalries between the two countries.
The American team, coached by Gregg Berhalter, are staying at the Marsa Malaz Kempinski on the Pearl, an artificial island north of Doha favored by expatriates.
They will train at the Al Gharafa club ground about 15 kilometers (nine miles) away.
The United States have played in 11 World Cups. They were third at the first tournament in 1930, famously beat England 1-0 at the 1950 World Cup and reached the quarter-finals in 2002.
They reached every finals from 1990 until 2014 but failed to get to Russia 2018.